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翻訳と辞書　辞書検索 [ 開発暫定版 ] スポンサード リンク Transposon mutagenesis ： ウィキペディア英語版 Transposon mutagenesis Transposon mutagenesis, or transposition mutagenesis, is a biological process that allows genes to be transferred to a host organism's chromosome, interrupting or modifying the function of an extant gene on the chromosome and causing mutation. Transposon mutagenesis is much more effective than chemical mutagenesis, with a higher mutation frequency and a lower chance of killing the organism. Other advantages include being able to induce single hit mutations, being able to incorporate selectable markers in strain construction, and being able to recover genes after mutagenesis. Disadvantages include the low frequency of transposition in living systems, and the inaccuracy of most transposition systems. ==History== Transposon mutagenesis was first studied by Barbara McClintock in the mid-20th century during her Nobel Prize-winning work with corn. McClintock received her BSc in 1923 from Cornell’s College of Agriculture. By 1927 she had her PhD in botany, and she immediately began working on the topic of maize chromosomes. In the early 1940s, McClintock was studying the progeny of self-pollinated maize plants which resulted from crosses having a broken chromosome 9. These plants were missing their telomeres. This research prompted the first discovery of a Transposable Element,〔 and from there transposon mutagenesis began becoming exploited as a biological tool. 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「Transposon mutagenesis」の詳細全文を読む スポンサード リンク 翻訳と辞書 : 翻訳のためのインターネットリソース Copyright(C) kotoba.ne.jp 1997-2016. All Rights Reserved.